comparing the efficacy of preemptive intravenous paracetamol on the reducing effect of opioid usage in cholecystectomy

نویسندگان

mustafa arslan department of anesthesiology and reanimation, gazi university medical faculty, ankara, turkey

bahadä±r celep departments of general surgery, yã¼ksek ihtisas hospital, kä±rä±kkale, turkey

ramazan ã‡iã§ek departments of general surgery, yã¼ksek ihtisas hospital, kä±rä±kkale, turkey

hã¼lya ãœstã¼n kalender departments of anesthesiology, yã¼ksek ihtisas hospital, kä±rä±kkale, turkey

چکیده

normal 0 false false false en-us x-none ar-sa background: the purpose of the present study was to determine the post-operative analgesic effects of preemptive intravenous (iv) paracetamol and the amount of reduction in tramadol (contramal ® ) consumption. materials and methods: following local research ethics committee approval, asai-ii, 300 patients were assigned in a randomized manner into three groups: group i (preemptive) received iv paracetamol 1 g/100 ml 10 min before skin inscision and 100 ml of saline solution at the end of the operation, group ii (post-operative) received 100 ml of saline solution 10 min before skin inscision and iv paracetamol 1 g/100 ml at the end of the operation and group iii (placebo) received 100 ml of saline solution 10 min before skin insicision and 100 ml of saline solution at the end of the operation as well. the time to first analgesic requirement use and 24 h total analgesic consumption were recorded . visual analog scale (vas) pain scores were obtained from all patients at 15, 30, min 1, 2, 4, 6, 8, 12 and 24 h after the end of the operation. results: time to first analgesic requirement was significantly longer in group i and group ii, compared to group iii ( p < 0.05). time to first analgesic requirement was significantly longer in group i compared to group ii ( p < 0.05). total analgesic consumption and postoperative vas pain scores recorded were significantly lower in group i and ii, compared to group iii. total analgesic consumption and postoperative vas pain scores recorded were significantly lower in group i compared to group ii ( p < 0.05). conclusion: in conclusion, preemptive iv paracetamol provided effective and reliable pain control after cholecystectomy surgeries and reduced post-operative pain scores, the need for and use of supplementary opioids and the time to first request of analgesics.

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منابع مشابه

Comparing the efficacy of preemptive intravenous paracetamol on the reducing effect of opioid usage in cholecystectomy

BACKGROUND The purpose of the present study was to determine the post-operative analgesic effects of preemptive intravenous (iv) paracetamol and the amount of reduction in tramadol (Contramal(®)) consumption. MATERIALS AND METHODS Following local research ethics committee approval, ASAI-II, 300 patients were assigned in a randomized manner into three groups: Group I (preemptive) received iv p...

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عنوان ژورنال:

journal of research in medical sciences

جلد ۱۸، شماره ۳، صفحات ۱۷۲-۰

کلمات کلیدی

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